It entirely depends on your cube and your vision for your cube.I am trying to cut down on removal spells - who should go?
I'm running GU(w) proliferate, and BG(u) self mill/recursion, so the latter two cards have some synergy.
'm running GU(w) proliferate, and BG(u) self mill/recursion
You are completely right. For example if you support combat tricks or auras than instant kill spells are very painful…It entirely depends on your cube and your vision for your cube.
Are you looking for simply going as high power as possible, then you can take out the worst performing card. Are you looking to have some synergy in your cube, you will have to do a lot more thinking. You will have to delve into what strategies the different decks have and cut the card that contributes to the fewest decks or cut the card that needs to be switched out for a better or worse card that does something similiar.
Example: Never//Return is good if you have some graveyard strategies in black. If you do not, then you can cut it.