Can you give some examples? Only thing that comes to my mind is
By Invitation Only.
Winds of Abandon is the only one I think I've put in an aggro deck, and I don't love how final it is, but it does fit the bill.
Delayed Blast Fireball has its issues (especially without other fortell in a cube) but it specifically does the thing
If you move up to midrange the space opens up:
Crippling Fear is really great at killing basically all but one creature on a board, and you can go harder to make it better for you.
Harvester of Misery (along with any ETB sweeper) leave you at least one creature, so they can work
Calamity of Cinders from the bloomburrow commander decks has other problems, but you can play this in your deck with 14 creatures in it for sure.
Any
Earthquake works, since you can sculpt it around your board size.
Flame Sweep/
Firespout is another cool idea with sculpting potential, and I prefer it over
Breath Weapon/
Fiery Cannonade for being easier to build around, but that could be fixed via the environment.
The Meathook Massacre probably maintains its price point via EDH players discovering this phenomenon.
Also its me, there are customs:
None of anything I've listed works
perfectly, but I much prefer an inconsistent sweeper that more than one drafter a night can put in their deck over another copy of wrath or 5 mana wrath plus.