I tend to agree with ravnic that racing and murder mystery are awkward flavor combos with MtG. If the cards would fit nicely into my cube I wouldn't care, but it actually does bother me when the pictures have funny hats and the creature types and names are detectives on cards that I might otherwise be interested in, like this:
I could run that, but it would bug me. The card flavor just feels stupid to me.
I do see why they want to mix things up with different worlds and themes. It would be hard to sell the same dragons and knights and zombies over and over.
There's a double flavor dissonance when they characters are doing a thing that isn't the regular wizard duels thing at the same time that the setting and art look like cowboys or horror movie Chuckie or whatever instead of wizards and warriors and demons.
They're gonna keep doing stuff like this, and I just won't cube the stuff I don't like.