Yeah, Woe-Reaper regularly grabs multiple cards in any combination of Mardu colors for my playgroup, and the life gain is significant as often as not, especially (again) in the somewhat suicidal aggro decks you tend to see reaper in.
EDIT: Also worth a mention in this capacity is Red Sun's Zenith. It's a weaker x-burn spell if evaluated in isolation at that capacity but has the exile clause and also shuffles your library (brainstorm, et all). And because it goes back in your library, you can draw it more than once in a game meaning it's worth slightly more than 1 removal spell.
Bump for recent investigation into GY hate in my own format. I feel like we haven't gotten many new toys since this thread was last being discussed, but there was one card I just found that seems to be a neat form of graveyard hate, and it is frustratingly unique too:
I really like:
Scrabbling Claws
Phyrexian Furnace
They cycle if it's irrelevant in a match. Triggers prowess, delirium, welder target, etc.
Thoughts on Relic of Progenitus?
The only problem I have with literally all of those is the repeatable effect doesn't target. Leaving it up to the opponent makes it quite a bit less effective to not use the "cycling" mode.
My wishlist card is a manarock with a second ability that's like "1, tap: exile target card + gain 1 life". Or something. But I really think a white card would be best.
Ooouu I forgot that existed. That is quite surgical and incidental, as well as being perfectly fine as Manalith besides. Neat.
One that I also hadn't considered very closely, but is quite interesting upon second look
It is the opposite of surgical, and it has that pesky let-your-opponent's-decide, but it only leaves 2 cards! This does a lot I like. It's colorless, so fits in any deck, it's effect isn't overly wanted by the GY shenanigans deck (as opposed to, say, Scavenging Ooze) leaving it open for red/white/etc decks to take it, and it doesn't outright stop single-use GY stuff, which hasn't been that burdensome anyway.
What if it had Replicate?