Its really weird being on the side, for once, questioning 4 mana sorcery speed spot removal, rather than defending it.
I just really don't see how it could be oppressive against a decent aggro deck, regardless of when you cast it. Sometimes I feel like the card reads "destroy target creature, gain 4 life, skip your turn." Usually with those types of cards I look for a bigger effect: consuming vapors, ribbons of night etc.
I still think the card should be run for its utility, but for actual removal i would much rather have a cheaper spell that lets me play multiple cards in a turn, rather than gain 4 life.